Book : Molecular Biology
posted by
Posted by: CHELSEA
posted by
Writer CHELSEA

Errors in DNA Replication

image about


Errors

The low overall rate of mutation during DNA replication (1 base pair change in one billion base pairs per replication cycle) does not reflect the true number of errors that take place during the replication process. The number is kept so low by a proof-reading system that checks newly synthesized DNA for errors and corrects them when they are found. Errors in DNA replication can take different forms, but usually revolve around the addition of a nucleotide with the incorrect base, meaning the pairing between the parent and daughter strand bases is not complementary. The addition of an incorrect base can take place by a process called tautomerization. A tautomer of a base group is a slight rearrangement of its electrons that allows for different bonding patterns between bases.



related articles

Helical Structure of DNA

Helical Structure of D...

  • Basics
  • posted Date:2017 Sep, 16

OverviewThe Helical Structure of DNA shows a single strand of DN...

read more
Denaturation and Renaturation

Denaturation and Renat...

  • Basics
  • posted Date:2017 Sep, 16

DenaturationDenaturation is the loss of a protein's or DNA's...

read more
Building Blocks of DNA Replication

Building Blocks of DNA...

  • Basics
  • posted Date:2017 Sep, 16

DeoxyribonucleotidesThe...

read more

Subscribe With Us For Daily Reading Lesson Materials